The MAD THINKER has improved the next generation of Super-Soldiers and they are here to finish the rampage of the RED SHE-HULK! Is Betty stuck in Omega Stage Hulk form forever? Will MACHINE MAN, SHE-HULK and humanity pay the price for Betty's interference in the future?
ROUTE 616 CONTINUES! Red She-Hulk goes deep underground to find the secrets of the ancient order of the Shield! There's a new ruler of the world below! He may never let her leave...
The issue that reveals that Betty Ross has more in common with Bruce Banner than the name HULK! The secret connection of Echelon and the end of humanity as the World Computer CRASHES! The last stand of MACHINE MAN!!!
The world's most powerful female superhuman is CLASSIFIED! Red She-Hulk's war on ALL superhumans continues! Captain America has no choice but to hunt her down! Will the newly redesigned X-51 need to use lethal force against her?
AN ALL-NEW ARC: ROUTE 616. Red She-Hulk is S.H.I.E.L.D.'s most wanted!!! Machine Man joins her on a deadly chase across the Marvel U! Jennifer Walters is hot on their trail!